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Many patients will require more than one drug to achieve blood pressure goals. There are no controlled trials demonstrating risk reduction with nebivolol tablets.Ĭontrol of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake.

These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including the class to which this drug principally belongs. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. Nebivolol tablets may be used alone or in combination with other antihypertensive agents.

Nebivolol tablets are indicated for the treatment of hypertension, to lower blood pressure.

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Sections or subsections omitted from the full prescribing information are not listed.

FULL PRESCRIBING INFORMATION: CONTENTS * 1 INDICATIONS AND USAGE 1.1 Hypertension 2 DOSAGE AND ADMINISTRATION 2.1 Hypertension 2.2 Subpopulations 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Abrupt Cessation of Therapy 5.2 Angina and Acute Myocardial Infarction 5.3 Bronchospastic Diseases 5.4 Anesthesia and Major Surgery 5.5 Diabetes and Hypoglycemia 5.6 Thyrotoxicosis 5.7 Peripheral Vascular Disease 5.8 Non-dihydropyridine Calcium Channel Blockers 5.9 Use with CYP2D6 Inhibitors 5.10 Impaired Renal Function 5.11 Impaired Hepatic Function 5.12 Risk of Anaphylactic Reactions 5.13 Pheochromocytoma 6 ADVERSE REACTIONS 6.1 Clinical Studies Experience 6.2 Laboratory Abnormalities 6.3 Postmarketing Experience 7 DRUG INTERACTIONS 7.1 CYP2D6 Inhibitors 7.2 Hypotensive Agents 7.3 Digitalis Glycosides 7.4 Calcium Channel Blockers 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy 8.2 Lactation 8.4 Pediatric Use 8.5 Geriatric Use 8.6 Heart Failure 10 OVERDOSAGE 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action 12.3 Pharmacokinetics 12.4 Pharmacokinetics in Special Populations 12.5 Drug-Drug Interactions 13 NONCLINICAL TOXICOLOGY 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility 14 CLINICAL STUDIES 14.1 Hypertension 16 HOW SUPPLIED/STORAGE AND HANDLING 17 PATIENT COUNSELING INFORMATION